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Page 1
Long-Term Safety and Efficacy of Eculizumab in Aquaporin-4 IgG-Positive NMOSD.
Wingerchuk DM, Fujihara K, Palace J, Berthele A, Levy M, Kim HJ, Nakashima I, Oreja-Guevara C, Wang KC, Miller L, Shang S, Sabatella G, Yountz M, Pittock SJ; PREVENT Study Group. Wingerchuk DM, et al. Ann Neurol. 2021 Jun;89(6):1088-1098. doi: 10.1002/ana.26049. Epub 2021 Feb 27. Ann Neurol. 2021. PMID: 33586143 Free PMC article. Clinical Trial.
A Randomized Trial of Intravenous Alteplase before Endovascular Treatment for Stroke.
LeCouffe NE, Kappelhof M, Treurniet KM, Rinkel LA, Bruggeman AE, Berkhemer OA, Wolff L, van Voorst H, Tolhuisen ML, Dippel DWJ, van der Lugt A, van Es ACGM, Boiten J, Lycklama À Nijeholt GJ, Keizer K, Gons RAR, Yo LSF, van Oostenbrugge RJ, van Zwam WH, Roozenbeek B, van der Worp HB, Lo RTH, van den Wijngaard IR, de Ridder IR, Costalat V, Arquizan C, Lemmens R, Demeestere J, Hofmeijer J, Martens JM, Schonewille WJ, Vos JA, Uyttenboogaart M, Bokkers RPH, van Tuijl JH, Kortman H, Schreuder FHBM, Boogaarts HD, de Laat KF, van Dijk LC, den Hertog HM, van Hasselt BAAM, Brouwers PJAM, Bulut T, Remmers MJM, van Norden A, Imani F, Rozeman AD, Elgersma OEH, Desfontaines P, Brisbois D, Samson Y, Clarençon F, Krietemeijer GM, Postma AA, van Doormaal PJ, van den Berg R, van der Hoorn A, Beenen LFM, Nieboer D, Lingsma HF, Emmer BJ, Coutinho JM, Majoie CBLM, Roos YBWEM; MR CLEAN–NO IV Investigators. LeCouffe NE, et al. N Engl J Med. 2021 Nov 11;385(20):1833-1844. doi: 10.1056/NEJMoa2107727. N Engl J Med. 2021. PMID: 34758251 Clinical Trial.
Anti-Inflammatory and Analgesic Effects of Rosehip in Inflammatory Musculoskeletal Disorders and Its Active Molecules.
Pekacar S, Bulut S, Özüpek B, Orhan DD. Pekacar S, et al. Curr Mol Pharmacol. 2021;14(5):731-745. doi: 10.2174/1874467214666210804154604. Curr Mol Pharmacol. 2021. PMID: 34348637 Review.
It is reported that the anti-inflammatory action mechanism of standardized rosehip powder is due to its antioxidant activity, inhibiting NF-B signaling and pro-inflammatory enzymes, decreasing inflammatory cytokine and chemokine production, and lowering C reactive protein levels. …
It is reported that the anti-inflammatory action mechanism of standardized rosehip powder is due to its antioxidant activity, inhibiting NF- …
The cytotoxicity and antioxidant activity analysis of the isolated constituents and extracts from endemic Centaurea derderiifolia.
Bulut F, Demirtas I, Koldas S, Gul F, Behcet L, Ozen T, Oke-Altuntas F. Bulut F, et al. Nat Prod Res. 2021 Jun;35(11):1919-1922. doi: 10.1080/14786419.2019.1644507. Epub 2019 Jul 23. Nat Prod Res. 2021. PMID: 31334668
The pure compounds were elucidated by spectroscopic and mass-spectrometric analyses, including 1 D-, 2 D-NMR. In addition to cytotoxic effects of the isolated constituents, their antioxidant activities were also studied. On the other hand, subfraction 4 exhibited th …
The pure compounds were elucidated by spectroscopic and mass-spectrometric analyses, including 1 D-, 2 D-NMR. In addition to c …
Possible Formation and Destruction of the OD+ Ions in the Interstellar Medium.
Bulut N, Roncero O, Lique F. Bulut N, et al. J Phys Chem A. 2020 Aug 13;124(32):6552-6561. doi: 10.1021/acs.jpca.0c05021. Epub 2020 Aug 4. J Phys Chem A. 2020. PMID: 32687711
In this paper, we aim at providing quantitative insight into the OD(+) chemistry and at accurately studying the possible formation and destruction processes of OD(+) in the ISM. We study the formation and destruction of OD(+) through the O(+) + HD OD(+) + H and OH(+) + …
In this paper, we aim at providing quantitative insight into the OD(+) chemistry and at accurately studying the possible formation and destr …
Prediction of Outcome and Endovascular Treatment Benefit: Validation and Update of the MR PREDICTS Decision Tool.
Venema E, Roozenbeek B, Mulder MJHL, Brown S, Majoie CBLM, Steyerberg EW, Demchuk AM, Muir KW, Dávalos A, Mitchell PJ, Bracard S, Berkhemer OA, Lycklama À Nijeholt GJ, van Oostenbrugge RJ, Roos YBWEM, van Zwam WH, van der Lugt A, Hill MD, White P, Campbell BCV, Guillemin F, Saver JL, Jovin TG, Goyal M, Dippel DWJ, Lingsma HF; HERMES collaborators and MR CLEAN Registry Investigators*. Venema E, et al. Stroke. 2021 Aug;52(9):2764-2772. doi: 10.1161/STROKEAHA.120.032935. Epub 2021 Jul 16. Stroke. 2021. PMID: 34266308 Free PMC article.
Hydrogen-bond-driven supramolecular helical assembly of a coumarin-substituted phthalonitrile derivative: synthesis and in vitro anticancer activity against colorectal adenocarcinoma.
Topkan F, Özdemir M, Özkan BN, Bozali K, Güler EM, Zorlu Y, Bulut M, Görgülü AO, Yalçın B. Topkan F, et al. Acta Crystallogr D Struct Biol. 2022 Sep 1;78(Pt 9):1143-1155. doi: 10.1107/S2059798322007823. Epub 2022 Aug 25. Acta Crystallogr D Struct Biol. 2022. PMID: 36048154
In this study, 7-hydroxy-4,8-dimethyl-3-pentylcoumarin (2) and its phthalonitrile derivative (2d) were crystallized; 2d crystallized in the rare trigonal space group R3. In the phthalonitrile derivative (2d), weak C-H...O hydrogen-bonding interactions promoted the formatio …
In this study, 7-hydroxy-4,8-dimethyl-3-pentylcoumarin (2) and its phthalonitrile derivative (2d) were crystallized; 2d crystallized in the …
Determinants of Symptomatic Intracranial Hemorrhage After Endovascular Stroke Treatment: A Retrospective Cohort Study.
van der Steen W, van der Ende NAM, van Kranendonk KR, Chalos V, van Oostenbrugge RJ, van Zwam WH, Roos YBWEM, van Doormaal PJ, van Es ACGM, Lingsma HF, Majoie CBLM, van der Lugt A, Dippel DWJ, Roozenbeek B; MR CLEAN Trial and MR CLEAN Registry Investigators. van der Steen W, et al. Stroke. 2022 Sep;53(9):2818-2827. doi: 10.1161/STROKEAHA.121.036195. Epub 2022 Jun 8. Stroke. 2022. PMID: 35674042 Free PMC article. Clinical Trial.
19 results